Title : Methyl methanesulfonate and hydrogen peroxide differentially regulate p53 accumulation in hepatoblastoma cells.

Pub. Date : 1999 Jun 1

PMID : 10403664






3 Functional Relationships(s)
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1 Methyl methanesulfonate and hydrogen peroxide differentially regulate p53 accumulation in hepatoblastoma cells. Methyl Methanesulfonate tumor protein p53 Homo sapiens
2 Since the mechanisms by which cellular DNA damaged by different DNA-damaging chemicals may not be the same, we studied the involvement of p53, Bcl-2 and Bax in apoptosis induced by methyl methanesulfonate (MMS) and hydrogen peroxide (H2O2). Methyl Methanesulfonate tumor protein p53 Homo sapiens
3 At non-lethal doses, both H2O2 and MMS induced high level of p53 protein accumulation. Methyl Methanesulfonate tumor protein p53 Homo sapiens