Title : Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication.

Pub. Date : 1999 Jun 15

PMID : 10403635






2 Functional Relationships(s)
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1 The acute toxicity of organophosphorus (OP) compounds in mammals is due to their irreversible inhibition of acetylcholinesterase (AChE) in the nervous system, which leads to increased synaptic acetylcholine levels. organophosphorus acetylcholinesterase Mus musculus
2 The acute toxicity of organophosphorus (OP) compounds in mammals is due to their irreversible inhibition of acetylcholinesterase (AChE) in the nervous system, which leads to increased synaptic acetylcholine levels. organophosphorus acetylcholinesterase Mus musculus