Pub. Date : 1999 Jul 16
PMID : 10400640
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The linkage of Kennedy"s neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator. | polyglutamine | RAN, member RAS oncogene family | Homo sapiens |
| 2 | Here we report the identification of a nuclear G-protein, Ras-related nuclear protein/ARA24, as the first AR coactivator that can bind differentially with different lengths of poly-Q within AR. | polyglutamine | RAN, member RAS oncogene family | Homo sapiens |
| 3 | In the yeast and mammalian reciprocal interacting assays, our data suggested the interaction of AR N-terminal domain with ARA24 diminishes as the poly-Q length increases. | polyglutamine | RAN, member RAS oncogene family | Homo sapiens |
| 4 | The coactivation of ARA24 also diminishes with the poly-Q expansion within AR. | polyglutamine | RAN, member RAS oncogene family | Homo sapiens |