Title : In vitro evaluation of aromatase enzyme in granulosa cells using a [11C]vorozole binding assay.

Pub. Date : 1999 Apr

PMID : 10399883






1 Functional Relationships(s)
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1 P450AROM concentrations measured by [11C]vorozole binding correlated positively with aromatisation of [1beta-3H]androst-4-ene-3,17-dione measured as [3H]water release, and a positive association was also found with the ovarian in vivo response to follicle-stimulating hormone (FSH) stimulation expressed as 1000 times the ratio of the number of oocytes recovered from a patient and the total dose of recombinant FSH administered. Androstenedione cytochrome P450 family 19 subfamily A member 1 Homo sapiens