Title : The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation.

Pub. Date : 1999 Jul

PMID : 10393704






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Conversion of alpha-amino acids to aldehydes requires hypochlorous acid (HOCl), formed from H2O2 and chloride by myeloperoxidase. Chlorides myeloperoxidase Homo sapiens
2 Furthermore, Nepsilon-(carboxymethyl)lysine (CML), a chemically well-characterized AGE product, was generated on RNase A when it was exposed to reagent HOCl-serine, the myeloperoxidase-H2O2-chloride system plus L-serine, or activated human neutrophils plus L-serine. Chlorides myeloperoxidase Homo sapiens