Title : Interleukin-6 production by activated human monocytic cells is enhanced by MK-571, a specific inhibitor of the multi-drug resistance protein-1.

Pub. Date : 1999 May

PMID : 10385244






2 Functional Relationships(s)
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1 MK-571 strongly enhanced IL-6 expression at mRNA and protein level in lipopolysaccharide (LPS) and interleukin-1 (IL-1) stimulated human monocytes giving rise to 2.0+/-0.4 (x+/-s.d.) verlukast interleukin 1 alpha Homo sapiens
2 MK-571 mediated upregulation of IL-6 in the presence of IL-1 was partially attenuated by SB203580 and PD98059. verlukast interleukin 1 alpha Homo sapiens