Pub. Date : 1999 Jul
PMID : 10383917
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | At the substrate concentration of 20 microM, which approximated the apparent KM value, sulfaphenazole (CYP2C9 inhibitor) and triazolam (CYP3A substrate) reduced the N-demethylation activities by 20 to 35% in human liver microsomes, whereas the inhibition induced by mephenytoin (CYP2C19 substrate) or quinidine (CYP2D6 inhibitor) was marginal. | Triazolam | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |