Title : Peptidyl beta-homo-aspartals (3-amino-4-carboxybutyraldehydes): new specific inhibitors of caspases.

Pub. Date : 1999

PMID : 10380358






1 Functional Relationships(s)
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1 (3) Unlike trypsin and thrombin (serine proteases), papain (cysteine protease) shows tolerance for D-stereochemistry at the P1 site of peptide aldehydes in proportion to the lability of the alpha-hydrogen of the P1-D-residue. Aldehydes coagulation factor II, thrombin Homo sapiens