Title : Cisplatin DNA cross-links do not inhibit S-phase and cause only a G2/M arrest in Saccharomyces cerevisiae.

Pub. Date : 1999 May 14

PMID : 10377946






1 Functional Relationships(s)
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1 However, other checkpoint mutants tested (mec1, mec3 and rad53) showed increased sensitivity to CDDP, as did controls with a defect in excision repair (rad1 and rad14) or a defect in recombination (rad51 and rad52). Cisplatin ssDNA endodeoxyribonuclease RAD1 Saccharomyces cerevisiae S288C