Pub. Date : 1999 Jul
PMID : 10373549
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, phosphopeptide maps of overexpressed PKB from COS cells showed differences between insulin- and forskolin-stimulated cells that pointed to distinct activation mechanisms of PKB depending on whether insulin or cAMP was used. | Colforsin | protein tyrosine kinase 2 beta | Homo sapiens |
| 2 | Moreover, phosphopeptide maps of overexpressed PKB from COS cells showed differences between insulin- and forskolin-stimulated cells that pointed to distinct activation mechanisms of PKB depending on whether insulin or cAMP was used. | Colforsin | protein tyrosine kinase 2 beta | Homo sapiens |
| 3 | Overexpression of a dominant negative PKB led to the loss of inhibition of GSK-3 in both insulin- and forskolin-treated cells, demonstrating that PKB was responsible for this inhibition in both cases. | Colforsin | protein tyrosine kinase 2 beta | Homo sapiens |
| 4 | Finally, we show by confocal microscopy that forskolin, similar to insulin, was able to induce translocation of PKB to the plasma membrane. | Colforsin | protein tyrosine kinase 2 beta | Homo sapiens |