Title : L-selectin interactions with novel mono- and multisulfated Lewisx sequences in comparison with the potent ligand 3'-sulfated Lewisa.

Pub. Date : 1999 Jun 25

PMID : 10373422






1 Functional Relationships(s)
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1 The binding to 3"-sialyl-Lex is strongly affected by the presence of 6-O-sulfate as found on oligosaccharides of the counter receptor, GlyCAM-1; 6-O-sulfate on the N-acetylglucosamine (6-sulfation) enhances, whereas 6-O-sulfate on the galactose (6"-sulfation) virtually abolishes binding. Acetylglucosamine fucosyltransferase 4 Homo sapiens