Title : Intravenous injection of an immunoconjugate (anti-PSA-IgG conjugated to 5-fluoro-2'-deoxyuridine) selectively inhibits cell proliferation and induces cell death in human prostate cancer cell tumors grown in nude mice.

Pub. Date : 1999 Mar-Apr

PMID : 10368631






2 Functional Relationships(s)
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1 We hypothesized that antibody immunoglobulin G (IgG) against human prostate specific antigen (PSA) (anti-PSA-IgG) could function as a carrier protein for conjugated chemotherapeutic drugs (such as 5-fluoro-2"-deoxyuridine, doxorubicin, etc.) Doxorubicin kallikrein related peptidase 3 Homo sapiens
2 We hypothesized that antibody immunoglobulin G (IgG) against human prostate specific antigen (PSA) (anti-PSA-IgG) could function as a carrier protein for conjugated chemotherapeutic drugs (such as 5-fluoro-2"-deoxyuridine, doxorubicin, etc.) Doxorubicin kallikrein related peptidase 3 Homo sapiens