Pub. Date : 1999 Jun 15
PMID : 10366427
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of vitamin D3 receptor in the synergistic differentiation of WEHI-3B leukemia cells by vitamin D3 and retinoic acid. | Tretinoin | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |
| 2 | No VDR was detected in untreated WEHI-3B D- cells; however, RA and 1,25-(OH)2D3 when used as single agents caused a slight induction of the VDR and in combination produced a marked increase in the VDR. | Tretinoin | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |
| 3 | No VDR was detected in untreated WEHI-3B D- cells; however, RA and 1,25-(OH)2D3 when used as single agents caused a slight induction of the VDR and in combination produced a marked increase in the VDR. | Tretinoin | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |
| 4 | These findings suggest that (a) induction of VDR expression is a key component in the synergistic differentiation induced by 1,25-(OH)2D3 and RA and (b) RAR and not RXR must be activated for enhanced induction of the VDR and for the synergistic differentiation produced by RA and 1, 25-(OH)2D3. | Tretinoin | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |
| 5 | These findings suggest that (a) induction of VDR expression is a key component in the synergistic differentiation induced by 1,25-(OH)2D3 and RA and (b) RAR and not RXR must be activated for enhanced induction of the VDR and for the synergistic differentiation produced by RA and 1, 25-(OH)2D3. | Tretinoin | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |
| 6 | These findings suggest that (a) induction of VDR expression is a key component in the synergistic differentiation induced by 1,25-(OH)2D3 and RA and (b) RAR and not RXR must be activated for enhanced induction of the VDR and for the synergistic differentiation produced by RA and 1, 25-(OH)2D3. | Tretinoin | vitamin D (1,25-dihydroxyvitamin D3) receptor | Mus musculus |