Title : Small effects of valproic acid on the plasma concentrations of clozapine and its major metabolites in patients with schizophrenic or affective disorders.

Pub. Date : 1999 Jun

PMID : 10365650






1 Functional Relationships(s)
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1 Overall, these findings suggest that valproic acid may have an inhibiting effect on the CYP1A2- or CYP3A4-mediated conversion of clozapine to norclozapine. norclozapine cytochrome P450 family 1 subfamily A member 2 Homo sapiens