Pub. Date : 1999 Jun 1
PMID : 10363974
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC-664704 (kenpaullone), is reported here to be a potent inhibitor of CDK1/cyclin B (IC50, 0.4 microM). | kenpaullone | cyclin dependent kinase 1 | Homo sapiens |
| 2 | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one, NSC-664704 (kenpaullone), is reported here to be a potent inhibitor of CDK1/cyclin B (IC50, 0.4 microM). | kenpaullone | cyclin dependent kinase 1 | Homo sapiens |
| 3 | Analogues of kenpaullone, in particular 10-bromopaullone (NSC-672234), also inhibited various protein kinases including CDKs. | kenpaullone | cyclin dependent kinase 1 | Homo sapiens |
| 4 | Kenpaullone represents a novel chemotype for compounds that preferentially inhibit CDKs. | kenpaullone | cyclin dependent kinase 1 | Homo sapiens |