Title : TNF-alpha and insulin, alone and synergistically, induce plasminogen activator inhibitor-1 expression in adipocytes.

Pub. Date : 1999 Jun

PMID : 10362602






2 Functional Relationships(s)
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1 Both superoxide (generated by xanthine oxidase plus hypoxanthine) and hydrogen peroxide were potent inducers of PAI-1, and hydroxyl radical scavengers completely abolished the TNF-alpha induction of PAI-1. Hydrogen Peroxide serpin family E member 1 Homo sapiens
2 Both superoxide (generated by xanthine oxidase plus hypoxanthine) and hydrogen peroxide were potent inducers of PAI-1, and hydroxyl radical scavengers completely abolished the TNF-alpha induction of PAI-1. Hydrogen Peroxide serpin family E member 1 Homo sapiens