Pub. Date : 1999 Apr
PMID : 10361889
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Anti-Fas antibody administration elevated CPP32-like protease activity at 3 hr in mouse liver, and this elevation of CPP32-like activity was inhibited by treatment with CsA. | Cyclosporine | caspase 3 | Mus musculus |
2 | Anti-Fas antibody administration elevated CPP32-like protease activity at 3 hr in mouse liver, and this elevation of CPP32-like activity was inhibited by treatment with CsA. | Cyclosporine | caspase 3 | Mus musculus |
3 | The present results show that CsA treatment inhibits the anti-Fas antibody-induced apoptotic process of hepatitis, at least in part, by affecting a reaction upstream of CPP32-like protease activation. | Cyclosporine | caspase 3 | Mus musculus |