Title : The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids.

Pub. Date : 1999

PMID : 10358761






3 Functional Relationships(s)
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1 The CD1 system: antigen-presenting molecules for T cell recognition of lipids and glycolipids. Glycolipids CD1c molecule Homo sapiens
2 Identification of naturally occurring antigens presented by CD1 has revealed the surprising finding that these are predominantly a variety of foreign lipids and glycolipids, including several found prominently in the cell walls and membranes of pathogenic mycobacteria. Glycolipids CD1c molecule Homo sapiens
3 Structural, biochemical, and biophysical studies support the view that CD1 proteins bind the hydrophobic alkyl portions of these antigens directly and position the polar or hydrophilic head groups of bound lipids and glycolipids for highly specific interactions with T cell antigen receptors. Glycolipids CD1c molecule Homo sapiens