Title : Cytotoxic analogs of luteinizing hormone-releasing hormone bind with high affinity to human breast cancers.

Pub. Date : 1999 Mar 1

PMID : 10355741






2 Functional Relationships(s)
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1 Recently, we developed two new cytotoxic analogs of luteinizing hormone-releasing hormone (LH-RH), AN-152 in which doxorubicin (DOX) is linked to [D-Lys6]LH-RH, and AN-207 which consists of 2-pyrrolino-DOX coupled to [D-Lys6]LH-RH. AN 204 gonadotropin releasing hormone 1 Homo sapiens
2 Recently, we developed two new cytotoxic analogs of luteinizing hormone-releasing hormone (LH-RH), AN-152 in which doxorubicin (DOX) is linked to [D-Lys6]LH-RH, and AN-207 which consists of 2-pyrrolino-DOX coupled to [D-Lys6]LH-RH. AN 204 gonadotropin releasing hormone 1 Homo sapiens