Title : Overexpression of calreticulin fails to abolish its induction by perturbation of normal ER function.

Pub. Date : 1998

PMID : 10353723






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ER stress induced calreticulin expression in response to either thapsigargin or tunicamycin was equivalent in these cells to that seen in control, nontransfected cells, leading us to conclude that calreticulin is unlikely be involved in its own induction. Tunicamycin calreticulin Homo sapiens
2 Levels of the mRNA encoding the fusion protein were also increased by tunicamycin, but not thapsigargin, suggesting that, in agreement with our previous observations, inhibition of N-linked glycosylation may increase the stability of calreticulin mRNA. Tunicamycin calreticulin Homo sapiens