Title : Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore.

Pub. Date : 1999 Apr 22

PMID : 10353597






1 Functional Relationships(s)
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1 Accordingly, the cell death-inducing effect of LND is amplified by simultaneous addition of PK11195, an isoquinoline ligand of the peripheral benzodiazepine receptor which antagonizes the cytoprotective effect of Bcl-2. isoquinoline BCL2 apoptosis regulator Homo sapiens