Pub. Date : 1999 May 15
PMID : 10346816
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. | Adenosine Triphosphate | RAD50 double strand break repair protein | Homo sapiens |
| 2 | On nonhairpin DNA ends, ATP controls a switch in endonuclease specificity that allows Mre11/Rad50/Nbs1 to cleave a 3"-protruding strand at a double-/single-strand transition. | Adenosine Triphosphate | RAD50 double strand break repair protein | Homo sapiens |
| 3 | Mutational analysis demonstrates that Rad50 is responsible for ATP binding by the complex, but the ATP-dependent activities are expressed only with Nbs1 present. | Adenosine Triphosphate | RAD50 double strand break repair protein | Homo sapiens |