Title : Biochemical mechanisms responsible for the attenuation of diabetic and obese conditions in ob/ob mice treated with dopaminergic agonists.

Pub. Date : 1999 Apr

PMID : 10340822






2 Functional Relationships(s)
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1 OBJECTIVE: We previously reported that a two week treatment with SKF 38393 (SKF, a dopamine D1 receptor agonist), plus bromocriptine (BC, a dopamine D2 receptor agonist) acted synergistically to normalize hyperphagia, body fat, hyperglycaemia and hyperlipidaemia in ob/ob mice. 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide dopamine receptor D1 Mus musculus
2 OBJECTIVE: We previously reported that a two week treatment with SKF 38393 (SKF, a dopamine D1 receptor agonist), plus bromocriptine (BC, a dopamine D2 receptor agonist) acted synergistically to normalize hyperphagia, body fat, hyperglycaemia and hyperlipidaemia in ob/ob mice. 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide dopamine receptor D1 Mus musculus