Title : Preservation of growth hormone secretion in response to growth hormone-releasing peptide-2 during prednisone therapy.

Pub. Date : 1999 May

PMID : 10337858






3 Functional Relationships(s)
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1 The pattern of GH release to arginine and to GHRP-2 was not identical, and the mean area under the curve for GH release to GHRP-2 decreased significantly with steroid treatment (P = .04), suggesting that GHRP-2 acts by mechanisms additional to the removal of SRIF inhibition. Steroids growth hormone 1 Homo sapiens
2 GH release occurred earlier for both arginine and GHRP-2 during steroid treatment. Steroids growth hormone 1 Homo sapiens
3 If GHRP-2 can indeed counteract the inhibitory effect of glucocorticoids on GH secretion, then a new form of therapy may be available to support growth in children who must receive long-term steroid treatment. Steroids growth hormone 1 Homo sapiens