Title : AMPA/kainate-related mechanisms contribute to convulsant and proconvulsant effects of 3-nitropropionic acid.

Pub. Date : 1999 Apr 16

PMID : 10334499






1 Functional Relationships(s)
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1 Moreover, 3-nitropropionic acid given in a subthreshold dose potently enhanced seizures generated by intracerebroventricular administration of AMPA and kainate, lowering their CD50 from 0.98 (0.83-1.17) and 0.73 (0.64-0.83) to 0.55 (0.45-0.66) (P<0.001) and 0.58 (0.51-0.65) (P<0.05) nmol, respectively. 3-nitropropionic acid intercellular adhesion molecule 5, telencephalin Mus musculus