Title : Newly discovered anti-inflammatory properties of the benzamides and nicotinamides.

Pub. Date : 1999 Mar

PMID : 10331648






1 Functional Relationships(s)
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1 Taken together these data strongly support the notion that benzamides and nicotinamides have potent anti-inflammatory and antitumor properties, because their primary mechanism of action is regulated by inhibition at the gene transcription level of NF-kappaB, which in turn inhibits TNFalpha and induces apoptosis. Niacinamide tumor necrosis factor Homo sapiens