Title : Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells.

Pub. Date : 1999 Mar

PMID : 10331635






1 Functional Relationships(s)
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1 To study the biological function(s) of poly(ADP-ribosyl)ation, we have established stable transfectants (COM3 cells) of the SV40-transformed Chinese hamster cell line C060 which conditionally overexpress the PARP DNA-binding domain upon addition of dexamethasone. poly(adp-ribosyl) poly (ADP-ribose) polymerase family, member 1 Mus musculus