Pub. Date : 1999 May
PMID : 10326169
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Weight gain and insulin resistance during nicotine replacement therapy. | Nicotine | insulin | Homo sapiens |
2 | Insulin sensitivity decreased by 14 +/- 2.6% during nicotine replacement but increased by 16 +/- 5.1% (compared with phase 2) during phase 3, even though the weight gain continued (p = 0.047; 95% confidence interval: 0.05-5.73). | Nicotine | insulin | Homo sapiens |
3 | Nicotine is the main ingredient in cigarette smoke causing insulin resistance, but the withdrawal of another, unknown ingredient in cigarette smoke is responsible for the weight gain associated with smoking cessation. | Nicotine | insulin | Homo sapiens |