Title : Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells.

Pub. Date : 1999 May

PMID : 10231436






2 Functional Relationships(s)
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1 Using similar incubation conditions, IL-1 also increased [3H]AA release from MCs. Tritium interleukin 1 alpha Homo sapiens
2 Pretreatment of MCs with aristolochic acid, a PLA2 inhibitor, concordantly reduced IL-1-regulated [3H]AA release and JNK1/SAPK activity, suggesting that cytosolic AA in part mediates IL-1-induced JNK1/SAPK activation. Tritium interleukin 1 alpha Homo sapiens