Pub. Date : 1999 Apr 30
PMID : 10222335
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ECE-1 and ECE-2 can be differentiated by pH dependence for optimal activity and by sensitivity to phosphoramidon, which shows selectivity for ECE-2 over ECE-1 and PD159790, a novel ECE-1 selective inhibitor. | phosphoramidon | endothelin converting enzyme 1 | Homo sapiens |
| 2 | ECE-1 and ECE-2 can be differentiated by pH dependence for optimal activity and by sensitivity to phosphoramidon, which shows selectivity for ECE-2 over ECE-1 and PD159790, a novel ECE-1 selective inhibitor. | phosphoramidon | endothelin converting enzyme 1 | Homo sapiens |
| 3 | ECE-1 and ECE-2 can be differentiated by pH dependence for optimal activity and by sensitivity to phosphoramidon, which shows selectivity for ECE-2 over ECE-1 and PD159790, a novel ECE-1 selective inhibitor. | phosphoramidon | endothelin converting enzyme 1 | Homo sapiens |
| 4 | In contrast, ECE activity was unaffected by 30 micromol/L PD159790 but was inhibited markedly by 0.1 and 100 micromol/L phosphoramidon at pH 5. | phosphoramidon | endothelin converting enzyme 1 | Homo sapiens |