Pub. Date : 1999 Mar 26
PMID : 10214966
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The addition of leucine induced activation of p70S6k in amino acid-depleted H4IIE cells. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 2 | Whereas the activation of p70S6k by leucine was transient, the complete amino acid stimulated p70S6k more persistently. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 3 | The effect of leucine on p70S6k was sensitive to rapamycin, but less sensitive to wortmannin. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 4 | Using various amino acids and derivatives of leucine, we found that the chirality, the structure of the four branched hydrocarbons, and the primary amine are required for the ability of leucine to stimulate p70S6k, indicating that the structural requirement of leucine to induce p70S6k activation is very strict and precise. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 5 | Using various amino acids and derivatives of leucine, we found that the chirality, the structure of the four branched hydrocarbons, and the primary amine are required for the ability of leucine to stimulate p70S6k, indicating that the structural requirement of leucine to induce p70S6k activation is very strict and precise. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 6 | Using various amino acids and derivatives of leucine, we found that the chirality, the structure of the four branched hydrocarbons, and the primary amine are required for the ability of leucine to stimulate p70S6k, indicating that the structural requirement of leucine to induce p70S6k activation is very strict and precise. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 7 | Using various amino acids and derivatives of leucine, we found that the chirality, the structure of the four branched hydrocarbons, and the primary amine are required for the ability of leucine to stimulate p70S6k, indicating that the structural requirement of leucine to induce p70S6k activation is very strict and precise. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 8 | Using various amino acids and derivatives of leucine, we found that the chirality, the structure of the four branched hydrocarbons, and the primary amine are required for the ability of leucine to stimulate p70S6k, indicating that the structural requirement of leucine to induce p70S6k activation is very strict and precise. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 9 | In addition, some leucine derivatives exhibited the ability to stimulate p70S6k and the other derivatives acted as inhibitors against the leucine-induced activation of p70S6k. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 10 | In addition, some leucine derivatives exhibited the ability to stimulate p70S6k and the other derivatives acted as inhibitors against the leucine-induced activation of p70S6k. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |
| 11 | In addition, some leucine derivatives exhibited the ability to stimulate p70S6k and the other derivatives acted as inhibitors against the leucine-induced activation of p70S6k. | Leucine | ribosomal protein S6 kinase B1 | Rattus norvegicus |