Pub. Date : 1999 Apr 12
PMID : 10209287
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A variety of sulphated polyanions in addition to heparin and dermatan sulphate stimulate the inhibition of thrombin by heparin cofactor II (HCII). | Dermatan Sulfate | serpin family D member 1 | Homo sapiens |
| 2 | A variety of sulphated polyanions in addition to heparin and dermatan sulphate stimulate the inhibition of thrombin by heparin cofactor II (HCII). | Dermatan Sulfate | serpin family D member 1 | Homo sapiens |
| 3 | Previous investigations indicated that the binding sites on HCII for heparin and dermatan sulphate overlap but are not identical. | Dermatan Sulfate | serpin family D member 1 | Homo sapiens |
| 4 | These results suggest that, like dermatan sulphate and heparin, other polyanions stimulate HCII primarily by an allosteric mechanism requiring the N-terminal acidic domain. | Dermatan Sulfate | serpin family D member 1 | Homo sapiens |