Pub. Date : 1999 Apr 21
PMID : 10208851
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of extended polyglutamine sequentially activates initiator and effector caspases. | polyglutamine | caspase 8 | Homo sapiens |
| 2 | This is the first direct evidence that the expression of extended polyQ activates caspases and together with the previous findings that some of the products of genes responsible for CAG repeat diseases are substrates of caspase-3 indicates an important role of caspases in the pathogenesis of these diseases. | polyglutamine | caspase 8 | Homo sapiens |
| 3 | This is the first direct evidence that the expression of extended polyQ activates caspases and together with the previous findings that some of the products of genes responsible for CAG repeat diseases are substrates of caspase-3 indicates an important role of caspases in the pathogenesis of these diseases. | polyglutamine | caspase 8 | Homo sapiens |