Title : Structure-affinity profile of 8-hydroxycarbostyril-based agonists that dissociate slowly from the beta2-adrenoceptor.

Pub. Date : 1999 Mar

PMID : 10208303






1 Functional Relationships(s)
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1 In addition, replacement of the 8-hydroxycarbostyril nucleus of 11a with catechol reduced the affinity of the compound for the beta2AR by 48-fold and increased its k(off). catechol beta-2 adrenergic receptor Mesocricetus auratus