Title : Effects of inflammatory mediators on gut sensitivity.

Pub. Date : 1999 Mar

PMID : 10202208






1 Functional Relationships(s)
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1 After local tissue injury, the release of chemical mediators such as potassium ions, ATP, bradykinin and prostaglandin E2 directly activate nerve endings and indirectly trigger the release of algesic mediators such as histamine, 5-hydroxytryptamine and nerve growth factor from other cells, which, in turn, stimulate proximal afferent nerve endings and silent nociceptors. Serotonin kininogen 1 Homo sapiens