Pub. Date : 1999 Apr
PMID : 10201532
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interleukin-4 deficient BALB/C mice sensitized to 2,4-dinitrochlorobenzene showed after challenge a significant reduction in magnitude and duration of the contact hypersensitivity response in comparison with wild-type mice. | Dinitrochlorobenzene | interleukin 4 | Mus musculus |
| 2 | This indicates that the contact hypersensitivity response to 2,4-dinitrochlorobenzene and Oxazolone may partly evolve on different pathways being dependent and independent of interleukin-4. | Dinitrochlorobenzene | interleukin 4 | Mus musculus |
| 3 | Our results clearly show that the complete loss of endogenous interleukin-4 expression in BALB/C mice is associated with an impaired manifestation of contact hypersensitivity response to 2,4-dinitrochlorobenzene, implying an important proinflammatory function of this cytokine. | Dinitrochlorobenzene | interleukin 4 | Mus musculus |