Title : Apoptosis in hematopoietic cells (FL5.12) caused by interleukin-3 withdrawal: relationship to caspase activity and the loss of glutathione.

Pub. Date : 1999 Jan

PMID : 10200549






1 Functional Relationships(s)
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1 Following IL-3 withdrawal, the caspase inhibitors z-VAD.fmk and boc-asp(OMe)fluoromethylketone (boc-asp.fmk) prevented the cleavage and activation of caspase-3, the breakdown of lamin B1 and partially mitigated PARP degradation. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone interleukin 3 Mus musculus