Pub. Date : 1999 Apr
PMID : 10200014
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: We have previously shown that the human recombinant histamine releasing factor (HrHRF) caused histamine release from a subset of basophils from donors with allergy, and this release seemed to be dependent on the presence of a certain type of IgE, termed IgE+. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 2 | BACKGROUND: We have previously shown that the human recombinant histamine releasing factor (HrHRF) caused histamine release from a subset of basophils from donors with allergy, and this release seemed to be dependent on the presence of a certain type of IgE, termed IgE+. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 3 | However, subsequently we demonstrated that HrHRF primes anti-IgE-antibody-induced histamine release from all basophils, irrespective of the type of IgE on the cell surface. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 4 | RESULTS: Mean anti-IgE-induced histamine release was 33% +/- 15%, and there was no difference between IgE+ sensitization (32% +/- 12%) and IgE- sensitization (34% +/- 18%). | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |