Title : CRKL binding to BCR-ABL and BCR-ABL transformation.

Pub. Date : 1999 Mar

PMID : 10194128






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The amino terminal CRKL SH3 domain binds directly to a proline-rich region in the C-terminus of BCR-ABL. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 Yeast two-hybrid analysis and gel overlay assays show eradication of the direct interaction of CRKL with BCR-ABL in the proline deletion mutants. Proline ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens