Pub. Date : 1999 Jan
PMID : 10191956
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Although inhibition of the Na+/Ca2+ exchanger normally increases [Ca2+]i in neonatal cardiac myocytes, application of the inhibitor Ni2+ appears to reduce [Ca2+] measured by fluo-3. | Nickel(2+) | nascent polypeptide associated complex subunit alpha 2 | Homo sapiens |
| 2 | Experiments with infected Sf9 cells suggested that Ni2+ was transported via the Na+/Ca2+ exchanger at a rate comparable to the Ca2+ transport. | Nickel(2+) | nascent polypeptide associated complex subunit alpha 2 | Homo sapiens |
| 3 | We conclude that Ni2+ does indeed block INaCa, but is also rapidly translocated across the cell membrane by the Na+/Ca2+ exchanger itself, most likely via an electroneutral partial reaction of the exchange cycle. | Nickel(2+) | nascent polypeptide associated complex subunit alpha 2 | Homo sapiens |