Title : Protein kinase inhibitor H7 blocks the induction of immediate-early genes zif268 and c-fos by a mechanism unrelated to inhibition of protein kinase C but possibly related to inhibition of phosphorylation of RNA polymerase II.

Pub. Date : 1999 Apr 9

PMID : 10187833






1 Functional Relationships(s)
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1 In these studies we confirmed that H7, but not HA1004, potently blocks the induction of zif268 and c-fos mRNA by nerve growth factor, carbachol, phorbol ester, Ca2+ ionophore, or forskolin. Carbachol Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus