Title : Oxidant-induced apoptosis in cultured human retinal pigment epithelial cells.

Pub. Date : 1999 Apr

PMID : 10102293






1 Functional Relationships(s)
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1 RESULTS: t-Butylhydroperoxide caused time- and dose-dependent activation of apoptosis in hRPE, indicated by characteristic morphologic changes; TUNEL-positive labeling; phosphatidylserine (PS) exposure; and procaspase 3, poly(ADP-ribose)polymerase, lamin, and tubulin cleavage. tert-Butylhydroperoxide caspase 3 Homo sapiens