Title : Uncompetitive inhibition of superoxide generation by a synthetic peptide corresponding to a predicted NADPH binding site in gp91-phox, a component of the phagocyte respiratory oxidase.

Pub. Date : 1999 Apr 2

PMID : 10092521






3 Functional Relationships(s)
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Protein Name
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1 Uncompetitive inhibition of superoxide generation by a synthetic peptide corresponding to a predicted NADPH binding site in gp91-phox, a component of the phagocyte respiratory oxidase. NADP cytochrome b-245 beta chain Homo sapiens
2 The large subunit of cytochrome b558, gp91-phox, is believed to play a key role in superoxide generation in neutrophils by accepting electrons from NADPH and donating them to molecular oxygen. NADP cytochrome b-245 beta chain Homo sapiens
3 We found that a peptide corresponding to a predicted NADPH binding site in gp91-phox inhibited superoxide generation in a cell-free system consisting of neutrophil membrane and cytosol. NADP cytochrome b-245 beta chain Homo sapiens