Title : Chronic ethanol consumption disrupts complexation between EGF receptor and phospholipase C-gamma1: relevance to impaired hepatocyte proliferation.

Pub. Date : 1999 Apr 2

PMID : 10092515






1 Functional Relationships(s)
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1 Tyrphostin AG1478, an EGFR-specific tyrosine kinase inhibitor, mimicked the effects of chronic ethanol on EGFR phosphorylation, PLC-gamma1 translocation and interactions between EGFR and PLC-gamma1 in the cytoskeleton. Tyrphostins epidermal growth factor receptor Rattus norvegicus