Pub. Date : 1999 Mar 26
PMID : 10085098
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here we demonstrate that methylmethane sulfonate (MMS)-induced activation of JNK is inhibited by overexpression of the anti-apoptotic protein Bcl-xL, but not by caspase inhibitors CrmA and p35. | Methyl Methanesulfonate | mitogen-activated protein kinase 8 | Homo sapiens |
2 | Here we demonstrate that methylmethane sulfonate (MMS)-induced activation of JNK is inhibited by overexpression of the anti-apoptotic protein Bcl-xL, but not by caspase inhibitors CrmA and p35. | Methyl Methanesulfonate | mitogen-activated protein kinase 8 | Homo sapiens |
3 | Hence, treatment of Bcl-xL cells with sodium vanadate, a tyrosine phosphatase inhibitor, restores MMS-induced activation of RAFTK and JNK. | Methyl Methanesulfonate | mitogen-activated protein kinase 8 | Homo sapiens |