Title : Organophosphorylation of acetylcholinesterase in the presence of peripheral site ligands. Distinct effects of propidium and fasciculin.

Pub. Date : 1999 Mar 26

PMID : 10085081






1 Functional Relationships(s)
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1 Kinetic rate constants were determined for the phosphorylation of AChE by two fluorogenic organophosphates, 7-[(diethoxyphosphoryl)oxy]-1-methylquinolinium iodide (DEPQ) and 7-[(methylethoxyphosphonyl)oxy]-4-methylcoumarin (EMPC), by monitoring release of the fluorescent leaving group. 7-[(methylethoxyphosphonyl)oxy]-4-methylcoumarin acetylcholinesterase (Cartwright blood group) Homo sapiens