Pub. Date : 1999 Feb
PMID : 10084649
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This E2-mediated growth stimulation was completely inhibited (cytostatic effects) by the epidermal growth factor receptor (EGFR)-selective tyrphostins A47, B48, RG13022, and B50. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |
2 | This E2-mediated growth stimulation was completely inhibited (cytostatic effects) by the epidermal growth factor receptor (EGFR)-selective tyrphostins A47, B48, RG13022, and B50. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |
3 | CONCLUSIONS: Of the agents tested, only EGFR-selective tyrphostins blocked E2-stimulated tumor cell proliferation, as opposed to the PDGFR-selective tyrphostin, RTK noninhibitory agent, or the phytoestrogen, genistein, which did not exert such an effect. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |
4 | CONCLUSIONS: Of the agents tested, only EGFR-selective tyrphostins blocked E2-stimulated tumor cell proliferation, as opposed to the PDGFR-selective tyrphostin, RTK noninhibitory agent, or the phytoestrogen, genistein, which did not exert such an effect. | Tyrphostins | epidermal growth factor receptor | Homo sapiens |