Title : p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis.

Pub. Date : 1999 Apr

PMID : 10082514






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 p70(S6K) activity is high in resting oocytes and decreases to background levels upon stimulation of maturation with progesterone. Progesterone ribosomal protein S6 kinase B1 L homeolog Xenopus laevis
2 Rapamycin, an inhibitor of p70(S6K) activation, caused oocytes to undergo germinal vesicle breakdown earlier than control oocytes, and sensitivity to progesterone was increased. Progesterone ribosomal protein S6 kinase B1 L homeolog Xenopus laevis