Pub. Date : 1999
PMID : 10080403
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of hepatocyte growth factor on tacrolimus-induced nephrotoxicity in spontaneously hypertensive rats. | Tacrolimus | hepatocyte growth factor | Rattus norvegicus |
| 2 | We investigated the effect of hepatocyte growth factor (HGF) on tacrolimus-induced nephrotoxicity in spontaneously hypertensive rats (SHR). | Tacrolimus | hepatocyte growth factor | Rattus norvegicus |
| 3 | We investigated the effect of hepatocyte growth factor (HGF) on tacrolimus-induced nephrotoxicity in spontaneously hypertensive rats (SHR). | Tacrolimus | hepatocyte growth factor | Rattus norvegicus |
| 4 | HGF significantly inhibited the tacrolimus-induced increase in the serum creatinine (SCr) level (P < 0.05). | Tacrolimus | hepatocyte growth factor | Rattus norvegicus |
| 5 | HGF also prevented the tacrolimus-induced loss in body weight. | Tacrolimus | hepatocyte growth factor | Rattus norvegicus |
| 6 | The bromodeoxyuridine (BrdU) index was significantly higher in kidney specimens from the tacrolimus + HGF group. | Tacrolimus | hepatocyte growth factor | Rattus norvegicus |
| 7 | These findings suggest that HGF induces the regeneration of renal tubular cells and suppresses tacrolimus-induced renal toxicity in SHR. | Tacrolimus | hepatocyte growth factor | Rattus norvegicus |