Pub. Date : 1999 Mar
PMID : 10078546
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cross-linking of Fas by anti-Fas resulted in the elevation of caspase-3-like, but not caspase-1-like, protease activity 2-12 h after the addition of the anti-Fas. | ammonium ferrous sulfate | caspase 3 | Mus musculus |
| 2 | The cross-linking of Fas by anti-Fas resulted in the elevation of caspase-3-like, but not caspase-1-like, protease activity 2-12 h after the addition of the anti-Fas. | ammonium ferrous sulfate | caspase 3 | Mus musculus |
| 3 | A caspase-3 inhibitor, Z-Asp-Glu-Val-Asp-fluoromethyl ketone, attenuated the Fas-mediated beta-cell apoptosis, while a caspase-1 inhibitor, acetyl-Tyr-Val-Ala-Asp-chloromethylketone, failed to suppress the apoptosis. | ammonium ferrous sulfate | caspase 3 | Mus musculus |
| 4 | These observations suggest the essential role of caspase-3 in Fas-mediated apoptosis of the beta-cell line. | ammonium ferrous sulfate | caspase 3 | Mus musculus |